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DonorIQ configured for research organ and tissue allocation
Research allocation for both organs and tissue operates under a different decision framework than clinical release. DonorIQ's matching layer was configured against research protocol criteria, producing structured allocation recommendations for coordinator review across both organ and tissue types.
The context
Organs and tissue that do not meet clinical release or transplant criteria are not necessarily unsuitable for research. Many procurement organizations maintain active research programs where donor organs and tissue that fall outside clinical thresholds still carry scientific value. But research allocation operates under a different decision framework than clinical use.
For clinical release or transplant, the question is structured around eligibility: does this donor case meet the criteria in the SOPs? For research allocation, the question is relational: does this donor organ or tissue match the requirements of an active research protocol, and is the intended use within the scope of that protocol?
The organization ran research allocation manually. A coordinator would review incoming organ and tissue availability, look across active research protocols, identify candidate matches based on type and donor attributes, and route the allocation recommendation to the appropriate research coordinator. When protocols changed, when new ones opened, or when a coordinator was unavailable, the matching step slowed or stalled.
What we configured
Research allocation required a configuration built from a different starting point than TissueQA. The matching layer was not referencing clinical eligibility SOPs. It was referencing research protocol specifications: organ and tissue type requirements, acceptable donor attribute ranges, exclusion criteria specific to each protocol's scientific objectives, and the documentation requirements of the receiving research institution.
A protocol intake structure was configured to load active research protocols into DonorIQ as the matching reference layer, covering both organ and tissue protocols. The system matches donor organs and tissue against currently active protocols rather than a static ruleset. Donor attribute extraction fields were tuned to research suitability, including organ- and tissue-specific attributes that clinical workflows do not always capture explicitly.
Coordinator routing was configured so that the matched allocation recommendation routes to the research coordinator responsible for the relevant protocol, with the supporting match evidence attached. The research coordinator's allocation decision — acceptance, modification, or rejection — is recorded against the DonorIQ output.
Capabilities deployed
- Custom matching layer configured against research protocol specifications for both organs and tissue
- Protocol intake structure supporting multiple active protocols simultaneously across organ and tissue types, updatable as protocols change
- Donor attribute extraction fields tuned to research-relevant organ and tissue characteristics
- Candidate allocation surfacing: for each organ or tissue, which active protocols it may satisfy and where it falls short
- PARTIAL and exclusion flag logic reflecting each protocol's specific exclusion criteria
- Coordinator routing based on protocol ownership, with match evidence delivered alongside the recommendation
- Research coordinator sign-off capture with allocation decision recorded against the AI-surfaced recommendation
- Audit trail recording protocol version, donor attributes, AI recommendation, and qualified human allocation decision
What the workflow now supports
Research coordinators receive structured allocation recommendations rather than manually compiled candidate matches. Each recommendation shows which protocol an organ or tissue may satisfy, which donor attributes support that match, and where the donor does not meet protocol requirements. Coordinators review the recommendation, confirm or adjust the allocation, and their decision is recorded against the DonorIQ output.
Protocol changes propagate into the matching layer when criteria are updated. The system works against currently active protocols rather than a fixed ruleset. The allocation record captures the protocol version that was active at the time of the decision.
This configuration does not make allocation decisions. It matches donor organs and tissue to protocol requirements, flags where requirements are not met, and routes the resulting recommendation to the human who holds the allocation authority for that protocol.
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